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Concerted actions of PRR- and NLR-mediated immunity.

Jack RhodesCyril ZipfelJonathan D G JonesBruno Pok Man Ngou
Published in: Essays in biochemistry (2022)
Plants utilise cell-surface immune receptors (functioning as pattern recognition receptors, PRRs) and intracellular nucleotide-binding leucine-rich repeat receptors (NLRs) to detect pathogens. Perception of pathogens by these receptors activates immune signalling and resistance to infections. PRR- and NLR-mediated immunity have primarily been considered parallel processes contributing to disease resistance. Recent studies suggest that these two pathways are interdependent and converge at multiple nodes. This review summarises and provides a perspective on these convergent points.
Keyphrases
  • cell surface
  • gram negative
  • antimicrobial resistance
  • multidrug resistant
  • early stage
  • transcription factor
  • radiation therapy
  • lymph node
  • binding protein