Time to Culture Conversion of Bedaquiline and High-Dose Isoniazid for Drug-Resistant Tuberculosis.

Kathleen Frances WalshStalz Charles VilbrunAriadne SouroutzidisJoshua EllisSobiesyke DelvaGuy JoissaintKathryn M DupnikPatrice JosephJean W PapeSerena P Koenig

Published in: Open forum infectious diseases (2022)

Patients with multidrug-resistant tuberculosis who received regimens containing high-dose isoniazid (INH HD ) had similar time to culture conversion and treatment outcomes as patients who received regimens with bedaquiline. INH HD is an inexpensive and safe medication that may contribute additive efficacy in combination regimens.

Keyphrases

drug resistant
multidrug resistant
high dose
mycobacterium tuberculosis
acinetobacter baumannii
gram negative
low dose
stem cell transplantation
pulmonary tuberculosis
klebsiella pneumoniae
adverse drug
healthcare
hiv aids
emergency department
escherichia coli
human immunodeficiency virus
pseudomonas aeruginosa