Sex ratio and age of onset in AQP4 antibody-associated NMOSD: a review and meta-analysis.
Simon V ArnettSin Hong ChewUnnah LeitnerJyh Yung HorFriedemann PaulMichael R YeamanMichael LevyBrian G WeinshenkerBrenda L BanwellKazuo FujiharaHesham AbboudIrena Dujmovic BasuroskiGeorgina ArrambideVeronika E NeubrandChao QuanEsther MelamedJacqueline PalaceCheng ChiNasrin AsgariSimon A Broadleynull nullPublished in: Journal of neurology (2024)
The female:male sex ratio and the mean age of onset of AQP4 antibody-associated NMOSD are significantly higher than MS. The sex ratio increases with the proportion of cases that are positive for AQP4 antibodies and the mean age of onset increases with population life expectancy.
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