Should adenosquamous esophageal cancer be treated like adenocarcinoma or squamous cell carcinoma?
Adriana C GamboaBenjamin I MeyerJeffrey M SwitchenkoManali RupjiRachel M LeeMichael K TurgeonMaria C RussellKenneth CardonaDavid A KoobyShishir K MaithelMihir M ShahPublished in: Journal of surgical oncology (2020)
Esophageal ASC behaves more like AC in response to chemoradiation and survival based on treatment modality. A complete response to chemoradiation is only 20% unlike what has been shown for SCC, where chemoradiation is an acceptable definitive therapy. Esophageal ASC should be managed more like AC.