Microbiota tryptophan metabolism induces aryl hydrocarbon receptor activation and improves alcohol-induced liver injury.
Laura WrzosekDragos CiocanCindy HugotMadeleine SpatzMargot DupeuxCamille HouronVanessa Lievin-Le MoalVirginie PuchoisValerio IebbaNicolas TrainelFrançoise Mercier-NoméSylvere DurandGuido KroemerCosmin Sebastian VoicanPatrick EmondMarjolène StraubeHarry SokolGabriel PerlemuterAnne-Marie CassardPublished in: Gut (2020)
Improvement of alcoholic liver disease by targeting the intestinal microbiota involves the AhR pathway, which should be considered as a new therapeutic target.