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Spectrum of LYST mutations in Chediak-Higashi syndrome: a report of novel variants and a comprehensive review of the literature.

Marie MorimotoElena-Raluca NicoliChulaluck KuptanonJoseph C RoneyJenny Serra-VinardellPrashant SharmaDavid R AdamsJohn I GallinSteven M HollandSergio D RosenzweigJose BarbotCarla CicconeMarjan HuizingCamilo ToroWilliam A GahlWendy J IntroneMay Christine V Malicdan
Published in: Journal of medical genetics (2023)
variants and improvements in variant classification will provide earlier diagnoses and improved care to individuals with CHS.
Keyphrases
  • copy number
  • healthcare
  • machine learning
  • palliative care
  • deep learning
  • quality improvement
  • case report
  • gene expression
  • dna methylation
  • genome wide