The importance of BRAF-V600E mutation to ameloblastoma metabolism.
Filipe Fideles Duarte-AndradeAndré Myller Barbosa SilvaJéssica Gardone VitórioGisele André Baptista CanutoSara Ferreira Santos CostaMarina Gonçalves DinizAna Paula FernandesJuliano Simões de ToledoLeiliane Coelho AndréCarolina Cavaliéri GomesHélder Antônio Rebelo PontesFlávia Sirotheau Correa PontesPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2019)
Ameloblastoma exhibits a distinct metabolic profile from normal odontogenic epithelium. BRAF-V600E may contribute to metabolic alterations in ameloblastoma. Collectively, our findings suggest that metabolic alterations might play a role in tumor pathogenesis.
Keyphrases