An E7-retinoblastoma protein pathway mechanism may account for the higher carcinogenic ability of HPV16 over HPV58 in cervical cancer.

Jian Zou Yang Li Tingting Chen Changkun Zhu

Published in: Translational cancer research (2024)

HPV16 possesses a stronger carcinogenic ability than does HPV 58, and the mechanism underlying this effect may be the impairment of the E7-Rb pathway.

Keyphrases

high grade
cervical cancer screening
polycyclic aromatic hydrocarbons
protein protein
binding protein