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An E7-retinoblastoma protein pathway mechanism may account for the higher carcinogenic ability of HPV16 over HPV58 in cervical cancer.

Jian ZouYang LiTingting ChenChangkun Zhu
Published in: Translational cancer research (2024)
HPV16 possesses a stronger carcinogenic ability than does HPV 58, and the mechanism underlying this effect may be the impairment of the E7-Rb pathway.
Keyphrases
  • high grade
  • cervical cancer screening
  • polycyclic aromatic hydrocarbons
  • protein protein
  • binding protein