Mesenchymal Stem Cells Alleviate Acute Liver Failure through Regulating Hepatocyte Apoptosis and Macrophage Polarization.

Yachao TaoYonghong WangMenglan WangHong TangEn-Qiang Chen

Published in: Journal of clinical and translational hepatology (2024)

hUC-MSCs could alleviate ALF by regulating hepatocyte apoptosis and macrophage polarization, thus hUC-MSC-based cell therapy may be an alternative option for patients with ALF.

Keyphrases

liver failure
cell therapy
mesenchymal stem cells
umbilical cord
hepatitis b virus
endoplasmic reticulum stress
cell cycle arrest
oxidative stress
cell death
bone marrow
stem cells
liver injury
drug induced
pi k akt
respiratory failure