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Idling for Decades: A European Study on Risk Factors Associated with the Delay Before a Narcolepsy Diagnosis.

Zhongxing ZhangYves DauvilliersGiuseppe PlazziGeert MayerGert Jan LammersJoan SantamariaMarkku PartinenSebastiaan OvereemRafael Del Río VillegasKarel SonkaRosa Peraita-AdradosRaphaël HeinzerAleksandra WierzbickaBirgit HöglMauro ManconiEva FeketeovaAntonio Martins da SilvaJitka BuškováClaudio L A BassettiLucie BarateauFabio PizzaElena AntelmiJari K GoolRolf FronczekCarles GaigRamin Khatami
Published in: Nature and science of sleep (2022)
Our findings contrast the results of previous studies reporting shorter delay over time which is confounded by calendar year, because they characterized the changes in diagnostic delay over the symptom onset year. Our study indicates that new strategies such as increasing media attention/awareness and developing new biomarkers are needed to better detect EDS, cataplexy, and changes of nocturnal sleep in narcolepsy, in order to shorten the diagnostic interval.
Keyphrases
  • obstructive sleep apnea
  • sleep quality
  • working memory
  • computed tomography
  • depressive symptoms
  • adverse drug
  • drug induced
  • patient reported