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Optimized photo-stimulation of halorhodopsin for long-term neuronal inhibition.

Chuanqiang ZhangShang YangTom FlossmannShiqiang GaoOtto W WitteGeorg NagelKnut HolthoffKnut Kirmse
Published in: BMC biology (2019)
Collectively, our findings extend the utility of eNpHR3.0 to the long-lasting inhibition of excitable cells, thus facilitating the optogenetic dissection of neural circuits.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • cell death
  • signaling pathway
  • visible light