Radiomics-Derived Brain Age Predicts Functional Outcome After Acute Ischemic Stroke.
Martin BretznerAnna K BonkhoffMarkus D SchirmerSungmin HongAdrian DalcaKathleen DonahueAnne-Katrin GieseMark R EthertonPamela M RistMarco NardinRobert W RegenhardtXavier LeclercRenaud LopesMorgan GautherotClinton WangOscar R BenaventeJohn W ColeAmanda DonattiChristoph GriessenauerLaura HeitschLukas HolmegaardKatarina JoodJordi Jiménez-CondeSteven J KittnerRobin LemmensChristopher R LeviPatrick F McArdleCaitrin W McDonoughJames F MeschiaChia-Ling PhuahArndt RolfsStefan RopeleJonathan RosandJaume RoquerTatjana RundekRalph L SaccoReinhold SchmidtPankaj SharmaAgnieszka SlowikAlessandro SousaTara M StanneStrbian DanielTurgut TatlisumakVincent N ThijsAchala VagalJohan WasseliusDaniel WooOna WuRamin ZandBradford B WorrallJane MaguireArne G LindgrenChristina JernPolina GollandGrégory KuchcinskiNatalia S RostPublished in: Neurology (2022)
T2-FLAIR radiomics can be used to predict brain age and derive RBA. Older appearing brains, characterized by a higher RBA, reflect cardiovascular risk factor accumulation and are linked to worse outcomes after stroke.