Infiltrative pattern of invasion is independently associated with shorter survival and desmoplastic stroma markers FAP and THBS2 in mucinous ovarian carcinoma.
Martin KoebelEun-Young KangSandra LeeTatjana TerzicAntony N KarnezisPrafull GhatageLawrence WooCheng-Han LeeNicola S MeagherSusan J RamusKylie L GorringePublished in: Histopathology (2023)
The pattern of invasion should be included in reporting for MOC due to the strong prognostic implications. We highlight the histological features that should be considered to improve reproducibility. FAP and THBS2 are associated with infiltrative invasion in MOC.