Subpopulations of Circulating Cells with Morphological Features of Malignancy Are Preoperatively Detected and Have Differential Prognostic Significance in Non-Small Cell Lung Cancer.
Emanuela FinaDavide FedericoPierluigi NovellisElisa DieciSimona MonterisiFederica CioffiGiuseppe MangiameliGiovanna FinocchiaroMarco AlloisioGiulia VeronesiPublished in: Cancers (2021)
Cancer cell hematogenous dissemination occurs frequently in patients with NSCLC without clinical evidence of distant metastases, laying the foundation for the application of cell-based tests in screening programs. CTC subpopulations are fine prognostic classifiers whose clinical validity should be further investigated in larger studies.
Keyphrases
- induced apoptosis
- small cell lung cancer
- single cell
- public health
- lymph node
- cell cycle arrest
- air pollution
- cell therapy
- stem cells
- bone marrow
- mesenchymal stem cells
- cell death
- high resolution
- mass spectrometry
- advanced non small cell lung cancer
- heat stress
- cell proliferation
- endoplasmic reticulum stress
- atomic force microscopy
- case control
- cell free