Comparative Safety of Targeted Therapies for Metastatic Colorectal Cancer between Elderly and Younger Patients: a Study Using the International Pharmacovigilance Database.

Amandine GouverneurPauline ClarazMarine RoussetMickaël ArnaudAnnie Fourrier-RéglatAntoine ParienteThomas AparicioGhada Miremont-SalaméPernelle Noize

Published in: Targeted oncology (2018)

ADRs related to targeted therapies used for mCRC treatment were different across age groups; yet, not systematically more reported or worse in elderly patients. Selected elderly patients could, therefore, be treated with these targeted therapies.

Keyphrases

metastatic colorectal cancer
newly diagnosed
end stage renal disease
adverse drug
prognostic factors
replacement therapy
patient reported
electronic health record