Login / Signup

Pharmacokinetics of doxorubicin following concomitant intravenous administration of olaratumab (IMC-3G3) to patients with advanced soft tissue sarcoma.

Victor M VillalobosGary MoMark AgulnikSeth M PollackDaniel A RushingArun SinghBrian Andrew Van TineRhian McNaughtonRodney L DeckerWei ZhangAshwin ShahirDamien M Cronier
Published in: Cancer medicine (2019)
Olaratumab at 15 or 20 mg/kg before doxorubicin infusion had no clinically relevant effect on systemic exposure to doxorubicin compared with doxorubicin alone in patients with metastatic or locally advanced STS.
Keyphrases
  • drug delivery
  • cancer therapy
  • locally advanced
  • squamous cell carcinoma
  • neoadjuvant chemotherapy
  • high dose
  • radiation therapy
  • drug induced