The effect of Jian Gan powder on the proliferation, migration and polarization of macrophages and relative mechanism.
Kun LiXue ZhengJian ZhangZhanpeng YanYu JiFei GeFangshi ZhuPublished in: Pharmaceutical biology (2024)
JGP effectively suppressed the cellular function of RAW264.7 cells by down-regulating the IL-6/STAT3 signaling pathway and modulating macrophage M1/M2 polarization. These findings provide valuable theoretical and experimental basis for considering the potential clinical application of JGP in the treatment of immune-mediated liver injury in clinical practice.