Targeted Proteins Reveal Cathepsin D as a Novel Biomarker in Differentiating Hepatocellular Carcinoma from Cirrhosis and Other Liver Cancers

Natthaya ChuaypenSupachaya SriphoosanaphanAthaya VorasitthaNutcha PinjaroenSakdithep ChaiyaritVisith ThongboonkerdPisit TangkijvanichPongserath Sirichindakul

Published in: Asian Pacific journal of cancer prevention : APJCP (2022)

Proteomics and subsequent validation revealed cathepsin D as a novel biomarker for HCC. Apart from its diagnostic role, serum cathepsin D might also serve as a prognostic biomarker of HCC. Additional large-scale studies are needed to verify our findings.

Keyphrases

single cell
mass spectrometry
genome wide
magnetic resonance imaging
computed tomography
magnetic resonance
dna methylation
young adults
contrast enhanced