Investigating the causal interplay between sleep traits and risk of acute myocardial infarction: a Mendelian randomization study.

Nikhil AroraLaxmi BhattaEivind Schjelderup SkarpsnoHåvard DalenBjørn Olav ÅsvoldBen Michael BrumptonRebecca Claire RichmondLinn Beate Strand

Published in: BMC medicine (2023)

This study reveals no interaction effects between sleep traits on the risk of AMI, but all combinations of sleep traits increased the risk of AMI except those with long sleep. This indicates that the main effects of sleep traits on AMI are likely to be independent of each other.

Keyphrases

acute myocardial infarction
sleep quality
physical activity
genome wide
percutaneous coronary intervention
left ventricular
heart failure
gene expression
dna methylation
acute coronary syndrome
atrial fibrillation