The Era of the FLips: How Spike Mutations L455F and F456L (and A475V) Are Shaping SARS-CoV-2 Evolution.

Daniele Focosi Pietro Giorgio SpeziaFederico GueliFabrizio Maggi

Published in: Viruses (2023)

Convergent evolution of the SARS-CoV-2 Spike protein has been mostly driven by immune escape, in particular by escape to the viral infection-neutralizing antibodies (nAbs) elicited by previous infections and/or vaccinations [...].

Keyphrases

sars cov
respiratory syndrome coronavirus
protein protein
amino acid
binding protein
coronavirus disease
zika virus
small molecule