Smoking-related changes in DNA methylation and gene expression are associated with cardio-metabolic traits.

Silvana C E MaasMichelle M J MensBrigitte KühnelJoyce B J van MeursAndré G UitterlindenAnnette PetersHolger ProkischChristian HerderHarald GrallertSonja KunzeMelanie WaldenbergerMaryam KavousiManfred KayserMohsen Ghanbari

Published in: Clinical epigenetics (2020)

Our study indicates that smoking-related changes in DNA methylation and gene expression are associated with cardio-metabolic risk factors. These findings may provide additional insights into the molecular mechanisms linking smoking to the development of CVD.

Keyphrases

dna methylation
gene expression
genome wide
smoking cessation
risk factors
copy number