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A family-based genome-wide association study reveals an association of spondyloarthritis with MAPK14.

Félicie CostantinoAlice TalpinRoula Said-NahalAriane LeboimeElena ZinovievaDiana ZelenikaIvo GutCéline CharonBrigitte IzacMichael WeissmanGilles ChiocchiaJohn D ReveilleMaxime BrebanHenri-Jean Garchon
Published in: Annals of the rheumatic diseases (2016)
We report here for the first time a family-based GWAS study on SpA and identified an associated polymorphism near MAPK14. Further analyses are needed to better understand the functional basis of this genetic association.
Keyphrases
  • genome wide association study
  • signaling pathway
  • oxidative stress
  • pi k akt
  • ankylosing spondylitis
  • gene expression
  • systemic lupus erythematosus