First steps towards combining faecal immunochemical testing with the gut microbiome in colorectal cancer screening.
Esmée J GrobbeeSuk Yee LamGwenny M FuhlerBlerdi BlakajSergey R KonstantinovMarco J BrunoMaikel P PeppelenboschErnst J KuipersManon Cw SpaanderPublished in: United European gastroenterology journal (2019)
These results show that the faecal microbial content can be measured in FIT samples and remains stable for six days. Total bacterial load was higher in colorectal cancer and high-grade dysplasia. These results pave the way for further research to determine the potential role of microbiota assessment in FIT screening.