Relating Glutamate, Conditioned, and Clinical Hallucinations via 1H-MR Spectroscopy.
Pantelis LeptourgosSonia BansalJenna DuttererAdam CulbrethAlbert R PowersPraveen SuthaharanJoshua KenneyMolly EricksonJames A WaltzS Andrea WijtenburgFrank GastonLaura M RowlandJames GoldPhilip Robert CorlettPublished in: Schizophrenia bulletin (2022)
Through computational psychiatry, we bridge a pathophysiological theory of psychosis (glutamate hypofunction) with a cognitive model of hallucinations (prior-overweighting) with implications for the development of new treatments for hallucinations.