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New oral liposomal vitamin C formulation: properties and bioavailability.

Maciej ŁukawskiPaulina DałekTomasz BorowikAleksander ForyśMarek LangnerWojciech WitkiewiczMagdalena Przybyło
Published in: Journal of liposome research (2019)
Vitamin C is the exogenous compound necessary for a variety of metabolic processes; therefore, the efficient delivery is critical for the maintenance of body homeostasis. Vitamin C pharmacokinetics and low quantities in processed foodstuff, necessitates its continuous supplementation. In the paper, we present the new liposomal formulation of vitamin C free of harmful organic solvents. The formulation was quantitatively characterized with respect to its chemically composition and nano-structuring. The vitamin C accessibility to cells from the formulation was evaluated using evidence derived from experiments performed on cell cultures. Finally, the enhanced bioavailability of vitamin C from the formulation was demonstrated in the medical experiment.
Keyphrases
  • drug delivery
  • healthcare
  • single cell
  • stem cells
  • ionic liquid
  • bone marrow