Study to investigate the prevalence of human papillomavirus in Barrett's oesophagus using a novel screening methodology.
Jonathan Richard WhiteKrish RagunathAimee WhittonElizabeth MarshPhilip KayeGillian KnightPublished in: BMJ open gastroenterology (2022)
This method can be used in BO's tissue to determine HPV infection. Adoption of this as a screening test could potentially revolutionise future research in this area. If a clear link between HPV and Barrett's dysplasia can be confirmed, this qPCR method has the potential to aid in monitoring and/or dysplasia detection by stratifying those most at risk and aid in the development of new therapies.