An Update on the Management of Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH).
Taymeyah Al-ToubahSimona Grozinsky-GlasbergJonathan R StrosbergPublished in: Current treatment options in oncology (2021)
DIPNECH is caused by an idiopathic proliferation of pulmonary neuroendocrine cells which can lead to bronchiolitis and multifocal lung neuroendocrine tumors. Patients often present with chronic cough and dyspnea. Larger NETs may develop malignant potential. Somatostatin analogs can palliate chronic symptoms, particularly cough. Surgical resection can be considered for relatively large (e.g. >1 cm), progressive tumors.
Keyphrases
- neuroendocrine tumors
- end stage renal disease
- pulmonary hypertension
- induced apoptosis
- newly diagnosed
- ejection fraction
- multiple sclerosis
- chronic kidney disease
- peritoneal dialysis
- cell therapy
- stem cells
- patient reported outcomes
- molecular docking
- cell proliferation
- cell death
- mesenchymal stem cells
- endoplasmic reticulum stress
- sleep quality
- respiratory syncytial virus