Whole-Brain Water Content Mapping Using Super-Resolution Reconstruction with MRI Acquisition in 3 Orthogonal Orientations.
Dennis C ThomasAna-Maria Oros-PeusquensDirk H J PootNadim Joni ShahPublished in: Magnetic resonance in medicine (2022)
Super-resolution reconstruction of multi-echo gradient echo data is demonstrated, enabling whole-brain water content mapping with high and isotropic resolution. The accuracy of the proposed method is shown using phantoms and 6 healthy volunteers and was found to be unchanged compared to the conventional acquisition. The proposed method could increase the sensitivity of water content mapping sufficiently to enable the detection of very small lesions, such as cortical lesions in multiple sclerosis.
Keyphrases
- multiple sclerosis
- high resolution
- white matter
- contrast enhanced
- diffusion weighted imaging
- magnetic resonance
- high density
- resting state
- magnetic resonance imaging
- diffusion weighted
- computed tomography
- cerebral ischemia
- big data
- mass spectrometry
- machine learning
- loop mediated isothermal amplification
- single molecule