Genetic and environmental risk structure of internalizing psychopathology in youth.

John M HettemaJessica L BourdonChelsea K SawyersBrad VerhulstMelissa A BrotmanEllen LeibenluftDaniel S PineRoxann Roberson-Nay

Published in: Depression and anxiety (2020)

Our findings suggest a complex latent genetic and environmental structure to ID phenotypes in youth. This structure, which incorporates both clinical symptoms and various psychological traits, informs future phenotypic approaches for identifying specific genetic and pathophysiological mechanisms underlying ID risk.

Keyphrases

genome wide
mental health
physical activity
copy number
young adults
dna methylation
current status
life cycle
depressive symptoms