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The Analysis of Pethidine Pharmacokinetics in Newborn Saliva, Plasma, and Brain Extracellular Fluid After Prenatal Intrauterine Exposure from Pregnant Mothers Receiving Intramuscular Dose Using PBPK Modeling.

Mo'tasem M AlsmadiNasir Idkaidek
Published in: European journal of drug metabolism and pharmacokinetics (2023)
It was shown that saliva can be used for pethidine TDM in newborns during the first few days after delivery to mothers receiving pethidine.
Keyphrases
  • pregnant women
  • white matter
  • resting state
  • gestational age
  • cord blood
  • low birth weight
  • multiple sclerosis
  • blood brain barrier
  • preterm birth