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Early squamous cell carcinoma of the oral tongue with histologically benign lymph nodes: A model predicting local control and vetting of the eighth edition of the American Joint Committee on Cancer pathologic T stage.

Shaum SridharanLester D R ThompsonBibianna PurginaCharles D SturgisAkeesha A ShahBrian BurkeyMadalina TulucDavid CognettiBin XuKevin HigginsJuan C Hernandez-PreraDominick GuerreroManish M BundeleSeungwon KimUmamaheswar DuvvuriMatthew J FerrisWilliam E GoodingSimion I Chiosea
Published in: Cancer (2019)
AJCC8 pT criteria resulted in pT upstaging of patients with pN0 disease without improved LR or LRR prognostication. The proposed model based on distance to the closest margin and perineural invasion, status outperformed pT as a predictor of LR and LRR in patients with early OTSCC.
Keyphrases
  • squamous cell carcinoma
  • lymph node
  • papillary thyroid
  • locally advanced
  • neoadjuvant chemotherapy
  • lymph node metastasis
  • cell migration
  • radiation therapy