Aberrant monocyte responses predict and characterize dengue virus infection in individuals with severe disease.
Yean K YongHong Y TanSoe Hui JenEsaki M ShankarSantha K NatkunamJameela SatharRishya ManikamShamala Devi SekaranPublished in: Journal of translational medicine (2017)
Given that the elevation IL-18, LBP and sCD14 among patients with severe form of dengue disease, our findings suggest a pathogenic role for an aberrant inflammasome and monocyte activation in the development of severe form of dengue disease.