Protective Effect of Galangin Methylation Modification Based on Cell Imaging on Inflammatory Lung Injury and Its Molecular Mechanism.

Ke HuYuxian LiLing JinYuefu ChenLijun ChenYingjun ZhangMinjiang HuangYan DingHuiming YinMinjiang Huang Bifeng Tan

Published in: Contrast media & molecular imaging (2022)

Galangin can interfere with the binding of transcription factors to inflammatory gene promoters through the methylation modification induced by PPAR/DNMT3A pathway, so as to inhibit the synthesis of inflammatory molecules and reverse inflammatory lung injury.

Keyphrases

oxidative stress
dna methylation
genome wide
transcription factor
gene expression
type diabetes
cell therapy
copy number
metabolic syndrome
genome wide identification
bone marrow