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Identifying aggressive prostate cancer foci using a DNA methylation classifier.

Kamilla MundbjergSameer ChopraMehrdad AlemozaffarChristopher DuymichRanjani LakshminarasimhanPeter W NicholsManju AronKimberly D SiegmundOsamu UkimuraMonish AronMariana SternParkash GillJohn D CarptenTorben F ØrntoftKarina D SørensenDaniel J WeisenbergerPeter A JonesVinay DuddalwarInderbir GillGangning Liang
Published in: Genome biology (2017)
Overall, this study provides molecular-based support for determining PC aggressiveness with the potential to impact clinical decision-making, such as targeted biopsy approaches for early diagnosis and active surveillance, in addition to focal therapy.
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