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The landscape of innate and adaptive immune cell subsets in patients with adult-onset Still's disease.

Huihui ChiXinyue HongNingqi DaiLongfang ChenHao ZhangHonglei LiuXiaobing ChengJunna YeHui ShiQiongyi HuJianfen MengZhuochao ZhouJinchao JiaTingting LiuFan WangMengyan WangYuning MaXia ChenYijun YouDehao ZhuZihan TangChengde YangJialin TengYutong SuYue Sun
Published in: Rheumatology (Oxford, England) (2023)
Our findings showed the activation of the innate and adaptive immune system in AOSD. The protein-protein interaction analysis suggested potential communication between innate and adaptive cell subsets. These findings provide new insights into the pathogenesis of the disease and the development of targeted therapies.
Keyphrases
  • immune response
  • protein protein
  • small molecule
  • single cell
  • peripheral blood
  • stem cells