Sex differences in the immune response to acute COVID-19 respiratory tract infection.

Shaohua QiConelius NgwaDiego A Morales ScheihingAbdullah Al MamunHilda W AhnstedtCarson E FingerGabriela Delevati ColpoRomana SharmeenYoungran KimHuiMahn A ChoiLouise D McCulloughFudong Liu

Published in: Biology of sex differences (2021)

Sex differences exist in hospitalized patients with acute COVID-19 respiratory tract infection. Exacerbated inflammatory responses were seen in male vs. female patients, even when matched for disease severity. Males appear to have a more robust innate immune response, and females mount a stronger adaptive immune response to COVID-19 respiratory tract infection.

Keyphrases

respiratory tract
immune response
coronavirus disease
sars cov
end stage renal disease
dendritic cells
newly diagnosed
toll like receptor
liver failure
respiratory syndrome coronavirus
prognostic factors
peritoneal dialysis
patient reported outcomes
intensive care unit