Topical application of autophagy-activating peptide improved skin barrier function and reduced acne symptoms in acne-prone skin.
Yoonjin LeeKayoung ShinKyong-Oh ShinSeokjeong YoonJuyeon JungEojin HwangHwa-Jee ChungAmir M HossiniChristos C ZouboulisMin Jeong BaekJi Hwoon BaekYoung Min ChiSang Eun LeeSekyoo JeongPublished in: Journal of cosmetic dermatology (2020)
Topical application of an autophagy activator downregulated sebaceous lipogenesis and improved the skin barrier function. Considering the important roles of sebum and skin barrier function in acne pathogenesis, autophagy activation might represent a new therapeutic option in early forms of acne.