Adverse drug reactions and associated factors in multidrug-resistant tuberculosis: A retrospective review of patient medical records at Mbarara Regional Referral Hospital, Uganda.
Oliver KushemererwaEdwin NuwagiraJoshua KiptooTadele Mekuriya YadesaPublished in: SAGE open medicine (2023)
Majority of patients with multidrug-resistant tuberculosis experience at least adverse drug reaction during the course of treatment. The newer standard shorter duration drug regimens (9-12 months) may be associated with intolerable adverse drug reactions that hamper effective management of multidrug-resistant tuberculosis. There is need for more studies to assess the clinical adverse drug reaction burden associated with the implementation of shorter duration regimens.
Keyphrases
- adverse drug
- multidrug resistant
- drug resistant
- gram negative
- acinetobacter baumannii
- electronic health record
- klebsiella pneumoniae
- healthcare
- emergency department
- primary care
- drug induced
- mycobacterium tuberculosis
- case report
- quality improvement
- risk factors
- hepatitis c virus
- hiv aids
- acute care
- antiretroviral therapy