Subclinical acute kidney injury is associated with adverse outcomes in critically ill neonates and children.
Fang FangXiaohan HuXiaomei DaiSanfeng WangZhenjiang BaiJiao ChenJian PanXiaozhong LiJian WangYanhong LiPublished in: Critical care (London, England) (2018)
Both initial and peak uCysC levels are associated with AKI and mortality and are independently predictive of mortality in critically ill neonates and children. Subclinical AKI may occur without detectable loss of kidney function, and uCysC-positive subclinical AKI is associated with worse clinical outcomes in this population.