Primary Failure Eruption: Genetic Investigation, Diagnosis and Treatment: A Systematic Review.

Inchingolo Francesco Irene Ferrara Fabio Viapiano Anna Maria CiociaIrene PalumboMariafrancesca Guglielmo Alessio Danilo Inchingolo Andrea PalermoIoana Roxana BordeaAngelo Michele Inchingolo Daniela Di Venere Gianna Dipalma

Published in: Children (Basel, Switzerland) (2023)

This systematic review provides valuable insights into the diagnosis, treatment, and genetic basis of PFE. Early diagnosis and personalized treatment planning are crucial for successful management. Genetic testing for PTH1R mutations aids in accurate diagnosis and may influence treatment decisions. However, further research is needed to explore the complex genetic basis of PFE fully and improve treatment outcomes for affected individuals.

Keyphrases

systematic review
genome wide
copy number
high resolution
gene expression
combination therapy