BRCA2 protects mammalian cells from heat shock.

Yosuke NakagawaAtsuhisa KajiharaAkihisa TakahashiAkiho S MurataMasaya MatsubayashiSoichiro S ItoIchiro OtaTakahiko NakagawaMasatoshi HasegawaTadaaki KiritaTakeo OhnishiEiichiro Mori

Published in: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group (2017)

BRCA2 has a protecting role against heat-induced cell death. BRCA2 might be a potential molecular target for hyperthermic cancer therapy.

Keyphrases

heat shock
cell death
cancer therapy
heat stress
breast cancer risk
drug delivery
heat shock protein
high glucose
oxidative stress
cell proliferation
climate change
human health
endothelial cells