Two Prenylated Chalcones, 4-Hydroxyderricin, and Xanthoangelol Prevent Postprandial Hyperglycemia by Promoting GLUT4 Translocation via the LKB1/AMPK Signaling Pathway in Skeletal Muscle Cells.

Kevin OdongoAyane AbeRina KawasakiKyuichi KawabataHitoshi Ashida

Published in: Molecular nutrition & food research (2024)

In conclusion, LKB1/AMPK pathway and subsequent GLUT4 translocation in skeletal muscle cells are involved in Ashitaba chalcone-suppressed acute hyperglycemia.

Keyphrases

skeletal muscle
induced apoptosis
signaling pathway
cell cycle arrest
insulin resistance
endoplasmic reticulum stress
pi k akt
liver failure
type diabetes
cell death
metabolic syndrome
epithelial mesenchymal transition
blood pressure
diabetic rats
respiratory failure
acute respiratory distress syndrome