Valve Academic Research Consortium 3: updated endpoint definitions for aortic valve clinical research.

null nullPhilippe GénéreuxNicolo Piazza Maria C Alu Tamim M Nazif Rebecca T Hahn Phillippe PibarotJeroen J BaxJonathon A LeipsicPhilipp BlankeEugene H Blackstone Matthew T FinnSamir KapadiaAxel LinkeMichael J MackRaj R MakkarRoxana MehranJeffrey J PopmaMichael ReardonJosep Rodes-CabauNicolas M Van MieghemJohn G WebbDavid Joel CohenMartin B Leon

Published in: European heart journal (2021)

Acknowledging the dynamic and evolving nature of less-invasive aortic valve therapies, further refinements of clinical research processes are required. The adoption of these updated and newly proposed VARC-3 endpoints and definitions will ensure homogenous event reporting, accurate adjudication, and appropriate comparisons of clinical research studies involving devices and new therapeutic strategies.

Keyphrases

aortic valve
transcatheter aortic valve replacement
transcatheter aortic valve implantation
aortic stenosis
aortic valve replacement
adverse drug
electronic health record
high resolution
heart failure
drug induced