Oxidative stress response in children undergoing cardiac surgery: Utility of the clearance of isoprostanes.
Stephanie HadleyDebora Cañizo VazquezMiriam Lopez AbadStefano CongiuDmytro LushchencovMarta Camprubí-CamprubíJoan Sanchez-de-ToledoPublished in: PloS one (2021)
Children undergoing CS, particularly neonatal patients, experience a significant post-operative OS response that might play an important role in postoperative morbidity. TGA patients undergoing arterial switch operations demonstrate the highest post-operative OS response. Rapid clearance of isoprostanes, which occurs more frequently in older patients with more mature antioxidant systems, might be associated with better clinical outcomes.
Keyphrases
- patients undergoing
- oxidative stress
- cardiac surgery
- end stage renal disease
- young adults
- chronic kidney disease
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- dna damage
- ischemia reperfusion injury
- patient reported outcomes
- diabetic rats
- middle aged
- induced apoptosis
- signaling pathway
- community dwelling
- patient reported
- endoplasmic reticulum stress
- quantum dots