HAP-FAST: a feasibility study incorporating qualitative, mechanistic and costing sub-studies alongside a randomised pilot trial comparing chest x-ray to low-dose CT scan and empirical antibiotics to antibiotics guided by the BIOFIRE® FILM ARRAY® pneumonia plus panel in adults with suspected non-ventilator-associated hospital-cquired pneumonia.
Natalia ShafiqaStephen AstonAlex HowardLance TurtleSimon AbramsBridget YoungFrances SherrattAnica Alvarez NishioStephanie WilshawAshley P JonesDaniel G WoottonPublished in: BMJ open (2024)
NCT05483309.
Keyphrases
- dual energy
- low dose
- computed tomography
- high resolution
- clinical trial
- image quality
- open label
- high dose
- healthcare
- respiratory failure
- pulmonary embolism
- double blind
- contrast enhanced
- positron emission tomography
- community acquired pneumonia
- systematic review
- study protocol
- magnetic resonance imaging
- acute care
- case control
- reduced graphene oxide
- emergency department
- magnetic resonance
- gold nanoparticles
- mass spectrometry
- extracorporeal membrane oxygenation
- pet ct
- drug induced