Treatment effects of intra-articular triamcinolone acetonide in an equine model of recurrent joint inflammation.
Clodagh M KearneyNicoline M KorthagenSaskia G M PlompMargot C LabbertéJanny C de GrauwP R van WeerenPieter A J BramaPublished in: Equine veterinary journal (2020)
In this model, intra-articular TA seems to have some anti-inflammatory activity (demonstrated by reductions in TP, WBCC and general MMP activity) up to 2 weeks post treatment but not at 4 weeks. This anti-inflammatory effect appeared to outlast a shorter-lived, potentially detrimental effect illustrated by increased synovial GAG and PGE2 levels after the first induction.
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