Discovery and Validation of a 15-Gene Prognostic Signature for Clear Cell Renal Cell Carcinoma.

Rohit MehraSrinivas NallandhighalBrittney CottaZayne KnuthFengyun SuAmy KasputisYuping ZhangRui Wang Xuhong CaoAaron M UdagerSaravana M Dhanasekaran Marcin P Cieslik Todd M Morgan Simpa S Salami

Published in: JCO precision oncology (2024)

We developed and validated a novel 15G prognostic signature to improve risk stratification of patients with ccRCC. Pending further validation, this signature has the potential to facilitate optimal treatment allocation.

Keyphrases

small molecule
high throughput
genome wide
gene expression
dna methylation
combination therapy
single cell
clinical evaluation
genome wide analysis