Potential for Maternally Administered Vaccine for Infant Group B Streptococcus.
Shabir Ahmed MadhiAnnaliesa S AndersonJudith AbsalonDavid RadleyRaphael SimonBabalwa JongihlatiRenate StrehlauAnika M van NiekerkAlane IzuNiree NaidooGaurav KwatraYogandree RamsamyMohamed SaidStephanie JonesLisa JoseLee FairlieShaun L BarnabasRyan NewtonSamantha MunsonZahra JefferiesDanka PavliakovaNatalie C Silmon de MonerriEmily GommeJohn L PerezDaniel A ScottWilliam C GruberKathrin U JansenPublished in: The New England journal of medicine (2023)
GBS6 elicited anti-CPS antibodies against group B streptococcus in pregnant women that were transferred to infants at levels associated with a reduced risk of invasive group B streptococcal disease. (Funded by Pfizer and the Bill and Melinda Gates Foundation; C1091002 ClinicalTrials.gov number, NCT03765073.).