Coronaviridae-Old friends, new enemy!
Igor Henrique Morais SilvaTeresa Paula de Lima GusmaoAdriana Machado ZarzarJair Carneiro Leao FilhoAndreza Barkokebas Santos de FariaIgor Henrique Morais SilvaLuiz Alcino Monteiro GueirosNarendran Andrew RobinsonStephen PorterAlessandra de Albuquerque Tavares CarvalhoPublished in: Oral diseases (2020)
Coronaviridae is a family of single-stranded positive enveloped RNA viruses. This article aimed to review the history of these viruses in the last 60 years since their discovery to understand what lessons can be learned from the past. A review of the PubMed database was carried out, describing taxonomy, classification, virology, genetic recombination, host adaptation, and main symptoms related to each type of virus. SARS-CoV-2 is responsible for the ongoing global pandemic, and SARS-CoV and MERS-CoV were responsible for causing severe respiratory illness and regional epidemics in the past while the four other strains of CoVs (229-E OC43, NL63, and HKU1) circulate worldwide and normally only cause mild upper respiratory tract infections. Given the enormous diversity of coronavirus viruses in wildlife and their continuous evolution and adaptation to humans, future outbreaks would undoubtedly occur. Restricting or banning all trade in wild animals in wet markets would be a necessary measure to reduce future zoonotic infections.
Keyphrases
- sars cov
- respiratory tract
- respiratory syndrome coronavirus
- current status
- genetic diversity
- machine learning
- small molecule
- escherichia coli
- deep learning
- dna damage
- coronavirus disease
- early onset
- genome wide
- high throughput
- dna methylation
- emergency department
- copy number
- physical activity
- single cell
- electronic health record