A novel variant in GLIS3 is associated with osteoarthritis.

Elisabetta CasaloneIoanna TachmazidouEleni ZenginiKonstantinos HatzikotoulasSophie HackingerDaniel SuvegesJulia SteinbergNigel William Raynernull nullJeremy Mark WilkinsonKalliope PanoutsopoulouEleftheria Zeggini

Published in: Annals of the rheumatic diseases (2018)

We identify a novel susceptibility locus for OA that has been previously implicated in diabetes and glycaemic traits.

Keyphrases

type diabetes
knee osteoarthritis
glycemic control
cardiovascular disease
rheumatoid arthritis
genome wide
genome wide association study
insulin resistance
dna methylation
adipose tissue
metabolic syndrome